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Children With FPIES Support Healthy Blood Pressure Safety Standards Needlesticks Multiple Sclerosis Cushing's Disease Neurologic Disease Rheumatoid Arthritis

Invasive Pests Solution

FPIES: What Is It And Could Your Child Have It?

pic(NAPSI)—What is FPIES?

FPIES is Food Protein Induced Enterocolitis Syndrome. It is commonly pronounced “F-Pies” and is a severe inflammation and reaction in the stomach and intestines. FPIES reactions often show up in the first weeks or months of life or at an older age for an exclusively breast-fed child.

Cow’s milk and soy products are the most common FPIES triggers, but many foods can cause an FPIES reaction, such as cereal grains, vegetables and chicken. Often confused with food allergies, since the reaction occurs only in the stomach and intestines with other organs being unaffected, it is a protein intolerance. This makes diagnosis difficult and often frustrating.

A child with FPIES may experience what appears to be a horrible stomach bug but the “bug” only starts a couple of hours after the offending food is given. Some children experience mild symptoms, while others have such severe vomiting and diarrhea that they can become seriously dehydrated and go into shock, which can result in seizures, shallow breathing and clammy skin.

FPIES reactions almost always start around two hours after eating the intolerable food and result in vomiting, commonly followed by diarrhea, which can last up to several days. If your child is experiencing severe symptoms of FPIES or shock, immediately call 911 first, as well as your child’s physician.

Diagnosis

It is common for FPIES to go undiagnosed for weeks to months, and the symptoms are often blamed on the stomach flu. FPIES is a newly recognized disease in the medical community, and unlike with common food allergies, standard tests are routinely negative in FPIES patients.

Keeping a food journal may be helpful in identifying food triggers if you think your child has FPIES, as diagnosis typically occurs based on food reaction history and physical examination.

“FPIES is often an underdiagnosed and misunderstood disorder. Due to limited research and a growing need for global awareness of this syndrome, many physicians struggle to accurately diagnose and treat FPIES patients. Physicians often confuse FPIES reactions with the flu or a common stomach virus,” said Fallon Schultz, founder, International Association for Food Protein Enterocolitis.

Treatment

Treating FPIES varies depending on the child; for some, treatment is avoiding the foods that cause vomiting and stomach pain.

“However, if your baby is diagnosed with FPIES, we recommend eliminating those specific infant formulas and food proteins from his diet and switching to an amino acid elemental formula like Neocate. Switching to a special formula like Neocate will help ensure that your baby gets the nutrients and calories he or she needs to grow and thrive,” says Steven Yannicelli, Ph.D., R.D., vice president of medical and scientific affairs for Nutricia North America.

Many children outgrow FPIES by age 3 but this can vary based on how severe their symptoms are and which foods they react to. To determine if your child has outgrown FPIES, it is important to work with your doctor and evaluate it on a food-by-food basis.

For more information, visit www.neocate.com.

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Olive leaf extract helps support healthy blood pressure

pic(NAPSI)—Good news for the aging baby boomer population and others: Blood pressure control is rated one of the most important health concerns and research shows that the bioactive compound oleuropein found in olive leaf extract helps support blood pressure. That’s important, considering high blood pressure is one of the most accurate predictors of cardiovascular disease, the No. 1 killer of Americans.

Many of the validated benefits of the Mediterranean diet derive from heart-healthy compounds contained in the olive fruit, including the polyphenols tyrosol and hydroxytyrosol. When it comes to olive’s power to support blood pressure already within a healthy range, research shows that the bioactive compound oleuropein is primarily responsible.

The Benefits

Oleuropein has been subjected to extensive research and found to have:

• A positive influence on LDL cholesterol

• A good influence on blood sugar levels already within normal range

• An ability to provide optimal support for cardiovascular health

• Powerful antioxidant properties to protect blood vessels against cellular damage caused by free radicals.

The Research

As published in the scientific journal Phytomedicine in February 2011, researchers using 1,000 mg per day of this formulation in a double-blind, randomized, parallel and active-controlled clinical trial documented an average 11.5 p mmHg (millimeters of mercury) decline in systolic readings. Systolic blood pressure is the maximum arterial pressure during the contraction of the left ventricle of the heart. In a blood pressure reading, the systolic pressure is typically the first number recorded. For example, with a blood pressure of 120 over 80, the systolic pressure is 120.

Where To Find It

Oleuropein is naturally found in olive leaves and also in a branded ingredient called Benolea from Frutarom, standardized to 16 percent oleuropein. Standardization is a process that manufacturers use to ensure consistency. In some cases, standardization involves identifying specific chemicals (known as markers). The process can also provide a measure of quality control.

Expert Advice

Life Extension Foundation®, a pioneer in funding cutting-edge research and reporting the latest anti-aging and integrative health therapies worldwide, suggests a daily serving of two 500-mg vegetarian capsules of Olive Leaf Vascular Support, a supplement product that supplies optimal concentrations of this proprietary, highly stable oleuropein, for maximum benefit.

Learn More

For more information about olive leaf extract and Olive Leaf Vascular Support, visit www.LEF.org/oliveleaf.

Free Magazine

You can sign up for a free, three-month subscription to Life Extension magazine at www.LifeExtension.com or by calling (800) 544-4440. It includes the latest global anti-aging research results and health news.


These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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Better Safety Standards For Healthcare Workers

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(NAPSI)—More than 5.6 million healthcare personnel in the U.S. are at risk of occupational exposure to blood-borne pathogens like HIV and hepatitis C. Needlestick injuries are sustained by 1,000 hospital employees alone each day. Countless more injuries occur in secondary-care facilities or go unreported. The financial costs to test and treat needlestick injuries exceed $1 billion a year, while the trauma caused to the victims and their loved ones is incalculable.

The federal government has previously introduced needlestick safety legislation requiring all U.S. healthcare facilities to protect their personnel wherever there is a risk of harm. Despite some improvements, significant challenges remain. For syringes and needles, the reported number of annual needlestick injuries has remained largely stable, with safety products responsible for the majority of incidents. Many government agencies and healthcare advocates desire equipment with passive (automatic) and fully integrated safety features that can virtually eliminate the risk of harm. Such preferred devices are rarely available for use.

Safe in Common is leading a Needlestick Safety Advocacy Campaign to raise industry awareness about delivering optimal protection to all healthcare personnel at risk from such injuries.

This year, Safe in Common will visit more than 50 hospitals and a dozen healthcare conferences across 36 metropolitan centers in the U.S. For more information about the tour and to sign a support pledge, visit www.safeincommon.org/pledge.

Safe in Common Chairperson Mary Foley said, “Firemen get fire-retardant clothing. Police get bulletproof vests. But healthcare personnel lack sufficient protection from needlestick injuries as they go about the daily business of enhancing and saving the lives of their patients. We believe that a needlestick injury should be a never-ever event.”

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MS Kills Connection > < Connection Kills MS

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(NAPSI)—Multiple sclerosis (MS), a chronic, unpredictable disease of the central nervous system, is known for destroying connections, but making connections is helping to defeat this disease.

MS disrupts signals within the brain and between the brain and the rest of the body. This disruption results in symptoms ranging from reduced mobility, to numbness and tingling, to cognition issues and abnormal fatigue, to blindness and paralysis.

While MS kills connection, connection can also kill MS. That’s why the National MS Society created the “MS Kills Connection > < Connection Kills MS” campaign: to forge connections among people with MS, people who treat those with MS and people who search for answers to create a world free of MS.

Such connections have helped move MS in less than two decades from being an untreatable disease to one for which there are at least eight treatment options for those with relapsing MS, the most common form of the disease. And there are now even more new therapies speeding through the pipeline that offer hope to people with all forms of the disease.

This effort to connect those who want to stop MS, restore nerve function damaged by MS and end the disease for all time is already leading to distinct victories:

• The International MS Genetics Consortium has discovered new MS risk genes;

• An international nervous system repair and protection initiative has led to one of the first adult stem cell clinical trials;

• Cross-organizational collaboration is being fostered through the MS Coalition and the Emerging Therapies Collaborative;

• The first worldwide Society-sponsored research initiative to find effective ways of treating progressive MS is under way;

• New and creative platforms to bring together top scientists are advancing research in the link between vitamin D and MS, in pediatric MS, and in quality-of-life strategies to improve long-term disease management outcomes.

To help foster connections among all those currently affected by MS or who may be affected in the future, the Society has introduced a multichannel public education campaign stressing the theme: “MS Kills Connection > < Connection Kills MS.”

Meredith Vieira is featured in this campaign along with her husband, Richard M. Cohen, who has MS. “You’re not in this alone,” she said. “We’re all in this boat.” Cohen added, “I deny the certainty of possible outcomes. It really frees you up.” To connect and help stop MS from shutting people down, you can visit www.MSconnection.org.


 

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Cushing’s Disease: Common Symptoms, Rare Disease

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(NAPSI)—Sometimes the simplest answer may not be the right one when it comes to health. When common symptoms point to a well-known cause, a more complicated underlying condition may be overlooked. Because of this, diagnosing rare diseases can be a challenge. For those affected by Cushing’s disease, a rare endocrine disorder, many signs and symptoms, including weight gain, depression, diabetes, fatigue and high blood pressure, are indistinguishable at first glance from other health conditions and often misdiagnosed. To raise awareness, Cushing’s Disease Awareness Day is celebrated annually on April 8—the birthday of Dr. Harvey Cushing, who was the first person to describe the disease.

Endocrine disorders occur when hormone levels are imbalanced. The most common endocrine disorder, diabetes, is associated with long-term complications that affect almost every part of the body. Though affecting only a small portion of the population, Cushing’s disease, like diabetes, can have enduring effects on the body. There are currently 39 people per million living with Cushing’s disease, while one to two people per million are diagnosed each year. It most commonly affects adults from 20 to 50 years old and affects women three to four times more often than men.

Cushing’s disease is the most common form of Cushing’s syndrome, a condition caused by excessive cortisol, a vital hormone that regulates metabolism, maintains cardiovascular function and helps the body respond to stress. In Cushing’s disease, the overproduction of cortisol is triggered by a noncancerous pituitary tumor. However, no known causes or risk factors have been identified for the development of the tumors that cause Cushing’s disease.

Since Cushing’s disease can be difficult to recognize and the process for accurate diagnosis is often lengthy, the time to diagnosis for a patient can be up to six years from the time they first notice symptoms. Patients with Cushing’s disease frequently see several doctors and undergo a variety of medical tests to accurately confirm a suspected diagnosis.

Lisa Wollman, from Massachusetts, knew that something was wrong beyond the simple symptoms. “Despite being active and eating right, I started to gain weight and often felt extremely tired. It took several years of medical testing and frequent visits to many different doctors before I was properly diagnosed with Cushing’s disease. I think it’s essential for you to pay attention to your body and be aware of the many symptoms, which may seem unrelated or insignificant but could be the key to helping your physicians reach a diagnosis.”

Although the symptoms of Cushing’s disease are broad and diverse, there are some characteristics that may help distinguish Cushing’s disease from other conditions, including rapid weight gain resulting in central obesity (abdomen that sticks out with thin arms and legs), having a “moon face” (round, red and full), purple stretch marks (striae), easy bruising and fractured bones.

Louise Pace, spokesperson for Cushing Support and Research Foundation, emphasizes the importance of disease awareness. “Living with a less common disorder like Cushing’s disease can be difficult for patients. The level of understanding needs to grow among both patients and doctors.”

To support Cushing’s Disease Awareness Day and patients worldwide, use Twitter and Facebook to post online resources, such as www.CushingsDisease.com, as well as information about the disease.

For more information about Cushing’s disease, please visit www.CushingsDisease.com.

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Learn About The Risks For A Rare Condition, Affecting Parkinson’s Patients And Others With Neurological Diseases

pic(NAPSI)—Patients who have neurological diseases, such as Parkinson’s disease, are no strangers to the difficulties that having a chronic disease can have on their daily lives. To make matters worse, many may be experiencing symptoms associated with the rare condition, neurogenic orthostatic hypotension (Neurogenic OH or NOH). A new survey of these patients and their caregivers revealed that 92 percent of patients have experienced at least one symptom of Neurogenic OH, but only 24 percent have ever heard of the condition.

Neurogenic OH occurs in people with an underlying neurologic diseases, such as Parkinson’s, multiple system atrophy (MSA), pure autonomic failure (PAF), nondiabetic autonomic neuropathy and dopamine beta hydroxylase deficiency. Of these patients, it’s estimated that Neurogenic OH affects 20−30 percent of Parkinson’s patients, 81 percent of MSA patients and nearly all of PAF patients. For people with Neurogenic OH, standing up from a sitting or lying position can lead to dizziness, lightheadedness, lack of concentration or vision problems.

Many of these symptoms, particularly dizziness, are persistent and may interfere with everyday life. Sometimes the dizziness and lightheadedness can even cause patients to fall unexpectedly, putting them at risk for other injuries. Many are forced to rely on others for extra help. Patients surveyed estimate they spend a significant amount of time, as many as eight hours per week, managing these symptoms.

“So many of these patients are overcome by the vast number of symptoms they experience every day,” says Judy Biedenharn, co-president, SDS/MSA Support Group. “As someone who spent years caring for a patient with MSA who displayed many of the symptoms associated with NOH, I can say that they impact every aspect of a patient’s life. Things like getting up from bed in the morning or walking up stairs can suddenly become an overwhelming task.”

But these patients aren’t alone in their day-to-day frustrations. Caregivers are deeply affected by the symptoms their loved ones are experiencing. Although caregivers estimate they spend nearly a full day every week (average of 22 hours) caring for a patient, many indicate they fear they are not doing enough to care for their loved ones. For example, 78 percent of caregivers worry that they do not catch every symptom that is being experienced.

If you or someone you are caring for has a neurologic disease and experiences any of these symptoms, visit www.SignsofNOH.com to learn more about the condition and download useful tools, such as a symptom assessment questionnaire. Patients and caregivers should talk to their physicians about what other conditions, such as Neurogenic OH, they may be susceptible to because of their neurological condition.

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Self-Injectable Treatment Option Available For Moderate To Severe Rheumatoid Arthritis

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(NAPSI)—ORENCIA® (abatacept) is the first and only biologic for the treatment of adults with moderate to severe rheumatoid arthritis (RA) available in both self-injectable (under the skin) and intravenous (IV) infusion (through a vein in the arm) formulations. Since the majority of RA patients initiating therapy with a biologic receive their treatment by self-injection, the availability of the self-injectable formulation of ORENCIA offers physicians a choice for more of their patients.

ORENCIA® (abatacept) is a prescription medicine that reduces signs and symptoms in adults with moderate to severe rheumatoid arthritis (RA), including those who have not been helped enough by other medicines for RA. ORENCIA may prevent further damage to your bones and joints and may help your ability to perform daily activities. In adults, ORENCIA may be used alone or with other RA treatments other than tumor necrosis factor (TNF) antagonists.

ORENCIA can also make your immune system less able to fight infections, so you may be more likely to get infections or any infection you have may get worse. It is important to tell your healthcare provider if you think you have any infections.

Important Safety Information: Serious Infections

ORENCIA can make you more likely to get infections or make the infection that you have get worse. Some patients have died from these infections. Call your healthcare provider immediately if you feel sick or get any of the following signs of infection: fever, feel very tired, cough, feel flu-like, or warm, red or painful skin.

“I talked with my doctor about the self-injectable formulation of ORENCIA and we discussed that weekly ORENCIA self-injection might be a good choice for me,” said Ray, a patient treated with ORENCIA IV. Patients should consult with their physician to see which treatment option is right for them.

Patients with RA can find that everyday tasks are much more difficult. Tasks like opening a car door, turning the handle on a faucet, buttoning a shirt or climbing stairs can become challenging.

Rheumatoid arthritis is a chronic, autoimmune disease characterized by inflammation in the lining of joints, causing joint damage with chronic pain, stiffness and swelling. RA causes limited range of motion and decreased joint function. The condition is more common in women, who account for 75 percent of patients diagnosed with RA.

ORENCIA is one treatment option indicated in adult patients with moderately to severely active RA and is intended for use under the guidance of a physician or healthcare practitioner. ORENCIA IV was approved for patients initiating therapy with a biologic in 2005. Since launch, more than 71,000 patients in the US have been prescribed ORENCIA IV.

For more information, talk to your doctor or visit www.ORENCIA.com and please read the Patient Information in the Full US Prescribing Information.

Please see the Important Safety Information that follows.

 

ORENCIA® (abatacept) Important Safety Information:

Indication and Usage

ORENCIA® (abatacept) is a prescription medicine that reduces signs and symptoms in adults with moderate to severe rheumatoid arthritis (RA), including those who have not been helped enough by other medicines for RA. ORENCIA may prevent further damage to your bones and joints and may help your ability to perform daily activities. In adults, ORENCIA may be used alone or with other RA treatments other than tumor necrosis factor (TNF) antagonists.

ORENCIA can also make your immune system less able to fight infections, so you may be more likely to get infections or any infection you have may get worse. It is important to tell your health care provider if you think you have any infections.

Important Safety Information About ORENCIA®) (abatacept)

Before you receive treatment with ORENCIA, a lyophilized powder for intravenous infusion or a solution for subcutaneous (under the skin) injection, you should tell your healthcare provider about all your medical conditions including if you:

• have any kind of infection even if it is small (such as an open cut or sore) or an infection that is in your whole body (such as the flu).

• have an infection that will not go away or a history of infections that keep coming back.

• have had tuberculosis (TB), a positive skin test for TB, or if you recently have been in close contact with someone who has had TB. If you get any of the symptoms of TB (a dry cough that does not go away, weight loss, fever, night sweats), call your healthcare provider right away. Before you start ORENCIA, your health care provider may examine you for TB or perform a skin test.

• have or have had viral hepatitis. Before you use ORENCIA, your health care provider may examine you for hepatitis.

• have a history of chronic obstructive pulmonary (lung) disease (COPD).

• are scheduled to have surgery.

• are allergic to any of the following ingredients in ORENCIA for infusion: abatacept, maltose, monobasic sodium phosphate, and sodium chloride for administration or the ingredients in ORENCIA injection: abatacept, sucrose, poloxamer 188, monobasic sodium phosphate monohydrate, dibasic sodium phosphate anhydrous, and water for injection.

• recently received a vaccination or are scheduled for any vaccination. If you are receiving ORENCIA, and for 3 months after you stop receiving ORENCIA, you should not take live vaccines.

• have diabetes and use a blood glucose monitor to check your sugar levels. The infusion of ORENCIA contains maltose, a sugar that can give falsely high blood glucose readings with some monitors on the day you receive your infusion. Your healthcare provider may tell you to use a different way to monitor your blood sugar levels. ORENCIA for subcutaneous injection (injected under the skin) does not contain maltose; therefore, you do not need to change the way you monitor your blood sugar if you are taking ORENCIA subcutaneously.

• are pregnant, planning to become pregnant, or are thinking about becoming pregnant. It is not known if ORENCIA can harm your unborn baby.

• are breast-feeding. You will need to decide to either breast-feed or receive treatment with ORENCIA, but not both.

• take any other kinds of medicine, including prescription and nonprescription medicines, vitamins and herbal supplements.

• are taking other biologic medicines to treat RA such as: Enbrel® (etanercept), Humira® (adalimumab), Remicade® (infliximab), Kineret® (anakinra), Rituxan® (rituximab), Simponi® (golimumab), Cimzia® (certolizumab pegol),

Actemra® (tocilizumab). You may have a higher chance of getting a serious infection if you take ORENCIA with other biologic medicines.

Possible Side Effects of ORENCIA® (abatacept)

ORENCIA can cause serious side effects including:

• Serious infections. ORENCIA can make you more likely to get infections or make the infection that you have get worse. Some patients have died from these infections. Call your health care provider immediately if you feel sick or get any of the following signs of infection: fever, feel very tired, cough, feel flu-like, or warm, red or painful skin.

• Allergic reactions. Allergic reactions can happen on the day of treatment or the day after receiving ORENCIA. Tell your healthcare provider or get emergency medical help right away if you have hives, swollen face, eyelids, lips, tongue or trouble breathing.

• Hepatitis B infection. If you are a carrier of the hepatitis B virus (a virus that affects the liver), the virus can become active while you use ORENCIA. Your healthcare provider may do a blood test before you start or while using ORENCIA.

• Vaccinations. You should not receive ORENCIA with certain types of vaccines. ORENCIA may cause some vaccinations to be less effective.

• Respiratory problems in patients with COPD. You may get certain respiratory problems more often if you receive ORENCIA and have COPD, including: worsened COPD, pneumonia, cough or trouble breathing.

• Cancer (malignancies). Certain kinds of cancer have been reported in patients receiving ORENCIA. It is not known if ORENCIA increases your chance of getting certain kinds of cancer.

Common side effects with ORENCIA are headache, upper respiratory tract infection, sore throat and nausea.

Please read the Patient Information in the Full US Prescribing Information.

© 2012 Bristol-Myers Squibb Company

ORENCIA is a registered trademark of Bristol-Myers Squibb. All other trademarks are property of their respective owners.

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Hungry Pests Threaten U.S. Agriculture

pic(NAPSI)—Imagine not having real maple syrup with your pancakes or orange juice to enjoy with breakfast. Or not relaxing under the shade of an ash tree with a glass of California wine. Invasive pests and diseases threaten so many things we hold dear.

If left unchecked, these “hungry pests” can affect many aspects of life—the fabric in clothing, food on the table, lumber used to build homes, flowers in the garden—and have already cost billions of dollars to the U.S. economy. Some can even hurt public health. The giant African snail can carry a parasite known to cause meningitis.

What Are Hungry Pests?

Invasive pests are any damaging insect, animal, plant or plant disease not native to an area. They have few or no natural enemies and can feed on or infect trees and plants in farms, forests, parks and backyards. Typically, people are unintentionally the No. 1 cause of invasive pests being brought into the country or spreading to new areas through the things they move and pack. The good news is that they can also be part of the solution.

What You Can Do

• Buy Local, Burn Local. Invasive pests and larvae can hide and ride long distances in firewood. Don’t give them a free ride—buy firewood where you burn it.

• Plant Carefully. Buy your plants from a reputable source and avoid using invasive plant species at all costs.

• Do Not Bring or Mail fresh fruits, vegetables or plants into your state or another state unless agricultural inspectors have cleared them beforehand.

• Cooperate with any agricultural quarantine restrictions and allow authorized agricultural workers access to your property for pest or disease surveys.

• Keep It Clean. Wash outdoor gear and tires between fishing, hunting or camping trips. Clean lawn furniture and other outdoor items when moving from one home to another.

• Learn To Identify. If you see signs of an invasive pest or disease, write down or take a picture of what you see and then report it at www.HungryPests.com/News.

• Speak Up. Declare all agricultural items to customs officials when returning from international travel. Call USDA to find out what’s allowed: (301) 851-2046 for plants, (301) 851-3300 for animals.

Help Stop Hungry Pests

Finally, tell your kids, neighbors and friends. The more people who know about invasive pests and the damage they cause, the better chance there is to prevent their spread. To see a growing list of these pests, the trees and crops being affected in the area and what you can do to help, visit www.HungryPests.com/News. You can help protect what you love.

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